The current and potential uses for surgical sealant products (glues, sealants, hemostats, anti-adhesion) varies by the clinical area and the type of benefit these products offer patients. These benefits range from the “important and enabling” in which their use provides potentially life-saving benefits compared to traditional wound sealing/closure products to those “aesthetic and perceived” benefits (e.g., reduced scarring) that are more cosmetic in nature.
We have assessed the potential global patient caseload that would benefit from these wound closure and sealant products along a spectrum from clinically necessary to aesthetically beneficial, in the following four categories:
Category I: Important and Enabling
Important to prevent excessive bleeding and transfusion, to ensure safe procedure, and to avoid mortality and to avoid complications associated with excessive bleeding and loss of blood.
Category II: Improved Clinical Outcome
Reduces morbidity due to improved procedure, reduced surgery time, and prevention of complications such as fibrosis, post-surgical adhesion formation, and infection (includes adjunct to minimally invasive surgery).
Category III: Cost-Effective and Time-Saving
Immediate reduction in surgical treatment time and need for follow-up treatments.
Category IV: Aesthetic and Perceived Benefits
Selection is driven by aesthetic and perceived benefits, resulting in one product being favored over a number of medically equivalent treatments.
Most importantly, we have assessed the sizes of the patient populations that are the targets of these different classes of clinical benefits by major clinical area. Below are illustrated, by both Clinical Area/Benefit and Benefit/Clinical Area, to illustrate the current and future volume of patient caseload for these novel wound closure and sealant products:
Surgical Procedures with Potential for the Use of Hemostats, Sealants, Glues and Adhesion Prevention Products, Worldwide (Millions), 2011
Source: Report #S190
Source: Report #S190