Skin securement (sealing, closure, hemostasis, etc.) has always been an essential final step in surgical procedures. In early years, the skin surface was sutured; in recent years a number of advances have been made, including new tapes, sutures, staples, hemostats, and glues.
Treatments for skin or dermal repair by surgical securement products represent a worldwide caseload of over 20 million annually. Burns represent the most serious of these cases, but roughly 25% of patients with burns die from them and overall are far fewer than ulcers. Ulcers, which may be caused by inadequate circulation, biochemical deficience or other causes, are a high volume, high cost caseload worldwide and, as such, drive considerable interest in the development of improved treatments. Nonetheless, the highest volume application in dermal repair in western civilization is plastic surgery.
Potential caseload is segmented by geography and skin repair type for the use of securement products, and is shown below:
Source: MedMarket Diligence, LLC; Report #S175, "Worldwide Surgical Sealants, Glues and Wound Closure, 2009-2013,"