Surgical Sealants in Cardiac Surgery Applications

Potential Cariovascular Sealants Patient IncidencesThe potential for surgical sealants in cardiovascular applications encompasses the major indications for use in surgical procedures involving peripheral valves, dysfunctional heart valves, congestive heart failure myocardial infarction and coronary heart disease, as shown in the figure at right. 

Cardiovascular disease is a major (and growing) public health problem in developed countries, representing a major outlay of healthcare expenditures. It is the highest cause of death in the

USA. Major multinational companies have targeted segments within this market and have promoted innovative solutions to both invasive and minimally invasive treatment of these disease states. These companies have also invested heavily in new procedures such as radiofrequency and transmyocardial laser revascularization, and biventricular pacing devices. In the future, adjunctive closure and securement products offer the potential to treat cardiovascular disease with products that aid the tissue repair process, encouraging faster recovery of surgical procedure site and donor sites.The increasingly ageing population, together with unhealthy dietary habits and a sedentary existence, are contributing to an expanded cardiovascular disease pool. The success of measures to prevent mortality from other diseases increases this effect. In addition, rising gross domestic product (GDP) is driving increasing surgical procedure uptake in developing countries. This means that the opportunity for new sealant, hemostasis and closure solutions in cardiovascular surgery offer a huge opportunity once new procedure-driven technical hurdles have been overcome.From “Worldwide Surgical Sealants, Glues & Wound Closure, 2007-2011.”  Report #S145.

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