Tissue ablation is predominantly cancer therapy

Tissue ablation is defined as the “removal of a body part or the destruction of its function, as by surgery, disease, or a noxious substance.” Put more simply, ablation is considered to be a therapeutic destruction and sealing of tissue.

The technologies representing the majority of physical (rather than chemical) ablation are comprised of the following:

  • Electrical
  • Radiation
  • Light
  • Radiofrequency
  • Ultrasound
  • Cryotherapy
  • Thermal (other than cryotherapy)
  • Microwave
  • Hydromechanical

Source: Report #A145, "Ablation Technologies Worldwide Market, 2009-2019: Products, Technologies, Markets, Companies and Opportunities."

The largest share of the market for energy-based ablation devices is used in cancer therapy, primarily using the radiation therapy modality. Following that is general surgery with its use of electrocautery and electrosurgical devices, RF ablation, cryotherapy, etc. Cardiovascular is thought to be third, even though cardiovascular is making the most noise in the medical press with RF and cryoablation of atrial fibrillation, this segment is thought to be third in share order. The remaining applications are relatively small and fall in line behind the three leading sectors.

Growth in the Asia/Pacific Market for Ablation Technologies

 

The Asia-Pacific market for ablation technologies looks quite different from the Americas and European Union. Here, at present, the largest market is Japan, which accounts for the majority of the market, although by population and current growth rates, the People’s Republic of China has the greatest potential. Its greater than 1.3 billion population and, more importantly, the healthcare infrastructure that the government is putting into place ensure that China will continue to comprise an ever greater share of this market.

Asia-pacific-ablation

Data in the exhibit is drawn from MedMarket Diligence report #A145, "Ablation Technologies Worldwide Market, 2009-2019: Products, Technologies, Markets, Companies and Opportunities."

 

 

Posted via email from medmarket's posterous


Until September 30, 2011, get any MedMarket Diligence report (any option: single user, site license or global license) for 20% off.  Order online (or any "online order" link) and use coupon code 1315780157 on checkout to receive a 20% discount.

 

Shifting caseload and markets in tissue ablation

Technologies to therapeutically ablate tissue (via destruction and/or removal of abnormal tissue or creation of a therapeutic lesion as in blocking errant electrical pathways in arrhythmia) represent a remarkably diverse set of tools despite their fundamentally common capability of tissue ablation.

Spanning electrical, radiation, light/laser, radiofrequency, ultrasound, cryotherapy, thermal therapy, microwave and hydromechanical and embodied in a wide range of medical devices and equipment, all ablation types simply destroy tissue.  The differences lie in respect to the specificity of each modality in targeting disease tissue and in respect to their capacity to be integrated in different types of instruments that may match the demands of specific clinical practices.

The recent history of ablation technology market developments reveals that, despite the specialization of modalities to specific tissues, or the efforts by manufacturers to carve out clinician or disease-state niches for specific modalities, growth in different ablation procedure types and clinical practice patterns has changed steadily but not always predictably.  Recent clinical results, new ablation device innovations and other developments have had the propensity to drive shifts in patient caseload between alternative ablation types.  Given the development and manufacturing costs, have largely and unsurprisingly maintained focus in typically one modality type, seeking to provide innovations in devices and equipment that accentuate benefits for there specific modality in specific clinical applications.

Below is illustrated the worldwide market for ablation technologies in 2009 and forecast 2019.

Source: "Ablation Technologies Worldwide Market, 2009-2019: Products, Technologies, Markets, Companies and Opportunities." Report #A145.

Evolution of ablation technologies and migration of caseload

Technologies to therapeutically ablate tissue (via destruction and/or removal of abnormal tissue or creation of a therapeutic lesion as in blocking errant electrical pathways in arrhythmia) represent a remarkably diverse set of tools despite their fundamentally common capability of tissue ablation.

Spanning electrical, radiation, light/laser, radiofrequency, ultrasound, cryotherapy, thermal therapy, microwave and hydromechanical and embodied in a wide range of medical devices and equipment, all ablation types simply destroy tissue.  The differences lie in respect to the specificity of each modality in targeting disease tissue and in respect to their capacity to be integrated in different types of instruments that may match the demands of specific clinical practices.

The recent history of ablation technology market developments reveals that, despite the specialization of modalities to specific tissues, or the efforts by manufacturers to carve out clinician or disease-state niches for specific modalities, growth in different ablation procedure types and clinical practice patterns has changed steadily but not always predictably.  Recent clinical results, new ablation device innovations and other developments have had the propensity to drive shifts in patient caseload between alternative ablation types.  Given the development and manufacturing costs, have largely and unsurprisingly maintained focus in typically one modality type, seeking to provide innovations in devices and equipment that accentuate benefits for there specific modality in specific clinical applications.

Below is illustrated the worldwide market for ablation technologies in 2009 and forecast 2019.

Source: "Ablation Technologies Worldwide Market, 2009-2019: Products, Technologies, Markets, Companies and Opportunities." Report #A145.

Ablation technologies and their variable penetration of clinical applications

Ablation technologies of different types have in common their ability to produce a therapeutic effect on human tissue.  Beyond this common ground, however, there are stark differences in the modalities.  Consequently, ablation technologies have variable penetration of clinical applications, with use of specific modalities for specific clinical applications driven by factors such as the tissue effect produced, likelihood of collateral tissue damage, the designs of manufacturers’ specific systems in meeting clinicians needs, cost, and other considerations. 

Cancer treatment is a good example, with a few modalities having significant shares of their worldwide ablation revenuesin cancer, while other modalities are little used in these areas. 

cancer-ablation

Source: MedMarket Diligence, LLC; Report #A125, "Worldwide Ablation Technologies."

 

 

Ablation technologies prolific in cancer treatment

Energy-based technologies and treatments exist for virtually all clinical specialties.  Given the ability of these technologies, particularly ablation technologies, to very precisely destroy tissue, they have been strongly developed for cancer applications and much success has already been achieved in producing treatments that have low risk, short recovery times and good long term outcomes.  Cost is non insignificant for these technologies, but thus far their clinical benefits have generally supported strong reimbursement.

Energy-based cancer treatment regimens consist of external beam radiation therapy, brachytherapy and a number of newer applications of energy therapies that ablate cancerous tissue. Prostate cancer for example, the most prevalent cancer among U.S. men, can now be treated with a range of energy based therapies that effectively supplement chemotherapy and other targeted therapeutics.
 

prostate-ablation

Souce: MedMarket Diligence, LLC, Report #A125: "Ablation Technologies Worldwide Market, 2008-2017: Products, Technologies, Markets, Companies and Opportunities."  See link for report description, detailed table of contents and list of exhibits.

The range of energy modalities used for ablation in cancer include the following:

  • brachytherapy
  • cryotherapy
  • microwave ablation
  • radiation therapy
  • radiofrequency (RF) ablation
  • stereotactic surgery
  • laser ablation
  • photodynamic therapy
  • ultrasonic ablation

As well, there are combinations of the above, and several of these (e.g., radiation therapy) have many variations in the way they can be delivered (note, for example, the overlap between brachytherapy, radiation therapy and stereotactic surgery).
 


Ablation Technologies Report #A125