Sealants, glues, hemostats, and other products in wound closure and securement offer benefits that vary by clinical area, but the nature of that benefit also varies by the type of end-point (benefit) the product achieves — does it provide a life-saving benefit? A time-saving? Cost-savings? A cosmetic or aesthetic benefit?
Accordingly, by examining the volume of procedures for which closure and securement products provide which kind of benefit is crucial to understanding demand, especially between competitive products.
Below is a categorization of benefits ranging from the critical (I) to the aesthetic (IV).
Criteria for Adjunctive Use of Hemostats, Sealants, Glues and Adhesion Prevention Products in Surgery
Source: MedMarket Diligence, LLC (Report #S192)
Considering these different categories, below are the volumes of procedures distributed by category across each of the major clinical disciplines.
Surgical Procedures with Potential for the Use of Hemostats, Sealants, Glues and Wound Closure Products, Worldwide (Millions), 2014
Source: MedMarket Diligence, LLC (Report #S192)
The growth in sales of a medical technology is dictated by a unique combination of a specific technology in a specific clinical application in a specific geographic market.
In the Smithers Apex report, “The Future of Tissue Ablation Products to 2020“, the markets for the different ablation technology types were assessed per application in each of the major world geographies. See the groupings, below:
Ablation Types and Clinical Applications:
- External Beam Radiation Therapy (EBRT)
- Cardiac & Vascular
- Oncologic Surgery
- GYN Surgery
- Dermal/Cutaneous Surgical
- Ophthalmic (Cataract) Surgical
- Multipurpose Surgical
- Urologic Surgical
- Multipurpose High Intensity Focused Ultrasound (HIFU)
- United States & Other Americas
- Largest Western & European States
- Major Asian States
- Rest of World
The Smithers Apex report contains the detailed assessment of ablation technology sales in each combination of technology, geography and clinical application. Below is illustrated graphically, sorted by compound annual growth rate in sales, each of the combinations.
Growth of Ablation Technologies by Clinical Application and Geography, 2014-2020
Source: Smithers Apex
Below is a list of the technologies under development at companies recently identified and included in the Medtech Startups Database.
- Handheld ultrasound, MRI imaging device.
- Needle-free injection drug delivery.
- Lenses designed to correct imbalance between eyes and brain that cause certain migraines.
- Continuous blood glucose monitoring in diabetes.
- Customized prosthetic aortic valve.
- Cystoscope-implanted, stent-like device to treat urinary obstruction associated with benign prostatic hypertrophy.
- Endovascular treatment for abdominal aortic aneurysm.
- Respiratory therapy device based on “high frequency chest wall oscillation” for treatment of COPD, other respiratory disorders.
- Treatment of arrhythmia.
- Medical device commercialization company active in cardiovascular care, tissue ablation, medical infusions, hand surgery and laparoscopic surgery.
- Surgical visualization systems.
- Arthroscopic bone tunneler and other orthopedic surgical instrumentation.
- Brain stimulation to treat multiple disorders.
See link for a month-by-month listing of the technologies at companies in the Medtech Startups Database.
Below is a list of the technologies under development at medical technology startups recently identified and included in the Medtech Startups Database.
- Prosthetic disc nucleus in spine surgery.
- Device and non-device technologies based on dynamics of blood flow.
- Magnetic and fluorescent technology point-of-care device to detect heart attack.
- Technologies for tissue reconstruction.
- Adult stem cell therapy in orthopedics, aesthetics, and chronic diseases (diabetes, COPD, heart disease, multiple sclerosis, stroke/cerebrovascular disease).
- Vagus nerve stimulation for neuromodulation treatment of various inflammatory autoimmune diseases.
- Surgical devices including for endoscopic access closure.
- Device to measure sympathetic nerve activity and produce ECG.
- Simultaneously track electrical measures that indicate brain, heart, optical and musculoskeletal activity.
- Needle-free pediatric withdrawal of blood.
- Ventilation systems for improved delivery of gas, moisture and nebulized medication.
- Broadly focused medical technology company active in osteoarthritis, cardiovascular, stroke, diabetes, infection control and spine surgery.
For a historical listing of technologies at medtech startups, see link.
Funding for medical technologies in October 2014 totaled $332 million, led by the $59 million funding of Ivantis, Inc., and the $55 million funding of PureTech.
Below are the top fundings for the month:
|Ivantis, Inc., has raised $58.87 million of a $71.37 million round of fundng according to a regulatory filing
||Stent-based treatment to lower intraocular pressure in glaucoma
|PureTech has raised $55 million in a round of funding according to the company
||Medical device and other technologies spanning treatments in immunology, metabolism, neuroscience, drug delivery and consumer digital health
|VytronUS, Inc., has raised $31.6 million in a Series B round of funding according to the company
||Integrated imaging and ultrasound ablation for treatment of cardiac arrhythmias
|Respicardia, Inc., has raised $25.09 million in a round of funding according to a regulatory filing
||Electrical pulse-based implant treatment for sleep apnea
|Magnus Life Science (Magnus Life Ltd) has raised £15.5 million ($24.96 million) in a round of funding according to regulatory filing
||Device and non-device technologies based on dynamics of bloodflow
|Medrobotics Corp. has raised $20 million in a preferred stock offering according to the company
||Computer-assisted access and visualization system for minimally invasive robotic surgery
For the complete list of medtech fundings in October 2014, see link. For a historical list of the fundings in medtech, by month, since 2009, see link.
Below is a list of new technologies under development at medtech startups recently identified and included in the Medtech Startups Database:
- Robotics for ophthalmic surgery.
- Dynamic force generation for bone repair.
- Neursurgical brain simulation system.
- Orthopedic technologies including pedicle screw that does not require a guide wire.
- Synthetic bone graft materials.
- Minimally invasive mitral valve replacement.
For a historical listing of the technologies under development at medtech startups, see link.
Below is a list of the technologies under development at newly identified medtech startups and included in the Medtech Startups Database.
- Technology for the repair of rotator cuff tears.
- Technologies for intravenous cannulation and phlebotomy, and an otorhinoscope.
- Implant for the treatment of urinary incontinence.
- LED (light) treatment of acute, dry macular degeneration.
- Esophageal cooling device to manage patient temperature.
- Surgical robotics.
- Patient positioning system for orthopedic surgery.
- Device to treat macular degeneration by delivering microcurrent to the eye.
For a historical listing of medtech startup technologies included in the database, see link.