Category Archives: medtech

topic is about medical technology of different types, describing specific products under development, the market for them or their impact on healthcare

Funding in medical technology, October 2014

Funding for medical technologies in October 2014 totaled $332 million, led by the $59 million funding of Ivantis, Inc., and the $55 million funding of PureTech.

Below are the top fundings for the month:

Company, funding Product/technology
Ivantis, Inc., has raised $58.87 million of a $71.37 million round of fundng according to a regulatory filing Stent-based treatment to lower intraocular pressure in glaucoma
PureTech has raised $55 million in a round of funding according to the company Medical device and other technologies spanning treatments in immunology, metabolism, neuroscience, drug delivery and consumer digital health
VytronUS, Inc., has raised $31.6 million in a Series B round of funding according to the company Integrated imaging and ultrasound ablation for treatment of cardiac arrhythmias
Respicardia, Inc., has raised $25.09 million in a round of funding according to a regulatory filing Electrical pulse-based implant treatment for sleep apnea
Magnus Life Science (Magnus Life Ltd) has raised £15.5 million ($24.96 million) in a round of funding according to regulatory filing Device and non-device technologies based on dynamics of bloodflow
Medrobotics Corp. has raised $20 million in a preferred stock offering according to the company Computer-assisted access and visualization system for minimally invasive robotic surgery

For the complete list of medtech fundings in October 2014, see link. For a historical list of the fundings in medtech, by month, since 2009, see link.

The relentless proliferation of wound closure technologies

Sutures are not dead. They cling to the wound closure market as tenaciously as, well, non-resorbable sutures.

Though the mainstay in the management of acute and traumatic surgical wounds for literally hundreds of years, sutures have been giving up some of their hold on the market, as a result of a robust rate of development, introduction and clinical acceptance of a wide array of biologically-based, chemically-based or combination of chem/bio products that stop bleeding, seal wound edges to varying degrees (adjunctively and independently) and otherwise close and heal wounds. The value of these products ranges from the critical, such as in new hemostat products with the potential to revolutionize treatment of battlefield wounds, to the aesthetic, with sealants that can dramatically reduce or eliminate scarring.

As the ancient Greek philosopher Heraclitus recognized, however, you cannot put your finger in the same river twice. The surgical arena continues to change dramatically and it challenges and creates enormous incentives for manufacturers to keep pace by developing novel wound closure technologies. Laparo-endoscopic innovations from conventional laparoscopy through single port laparoscopy to natural orifice transluminal endoscopic surgery established new requirements for the manipulation of tissue and manufacturers responded with a wide range of endoscopic sutures, staples, clips and appliers to facilitate MIS procedures.  Even sutures themselves have been reengineered to dissolve in controlled ways to enhance the end result of wound closure.

But where sutures were once THE universally accepted manner to bring wound margins together, they are now challenged on all sides by fibrin and other surgical sealants, hemostatic agents, vascular closure devices, cyanoacrylate and other high strength surgical glues and even sophisticated tapes. For now, sutures hold the slim margin of dominance in this aggregate market, but by 2018, the overall market for wound closure will be represented in the majority, by products other than surgical sutures and staples:

Worldwide Surgical Wound Closure Products Market, by Device Segment, 2018

closure-shares-2018

Source: MedMarket Diligence, LLC; Report #S192

 

New Medical Technologies at Startups, September 2014

Below is a list of new technologies under development at medtech startups recently identified and included in the Medtech Startups Database:

  • Robotics for ophthalmic surgery.
  • Dynamic force generation for bone repair.
  • Neursurgical brain simulation system.
  • Orthopedic technologies including pedicle screw that does not require a guide wire.
  • Synthetic bone graft materials.
  • Minimally invasive mitral valve replacement.

For a historical listing of the technologies under development at medtech startups, see link.

New Medical Technology Fundings, September 2014

Fundings in medical technology for the month of September 2014 stand at $421 million, led by the $46 million funding of Vital Therapies. Below are the top fundings for the month thus far.

Company, funding Product/technology
Vital Therapies, Inc., has raised $46 million in a public stock offering according to press reports Technologies for the regeneration of liver tissue
Fractyl Laboratories, Inc., has raised $40 million in a Series C round of funding according to a regulatory filing Endoscopic device to aid in type 2 diabetes glucose management
Corindus Vascular Robotics, Inc., has raised $26.67 million in a round of funding according to a regulatory filing Robotic system to assist interventional cardiologists with stent placement
Acutus Medical, Inc., has raised $26.2 million in a Series B round of funding, according to press reports Minimally invasive, 3D cardiac imaging/mapping technology
iHealth Lab has raised $25 million from Xiaomi Ventures, according to press reports Wireless blood-pressure and blood-glucose monitoring
Ivantis, Inc., has raised $25 million adding to its existing Series B round of funding according to press reports Device for the treatment of glaucoma
Minerva Surgical, Inc., has raised $25 million in a round of funding according to a regulatory filing Ablation device for the treatment of menorrhagia
REVA Medical, Inc., has raised $25 million in new funding according to the company Bioresorbable scaffold for use in vascular stents

For the complete list of medtech fundings in September 2014, see link. For a historical list of the fundings in medtech, by month, since 2009, see link.

New Technologies Under Development at Medtech Startups, August 2014

Below is a list of the technologies under development at newly identified medtech startups and included in the Medtech Startups Database.

  • Technology for the repair of rotator cuff tears.
  • Technologies for intravenous cannulation and phlebotomy, and an otorhinoscope.
  • Implant for the treatment of urinary incontinence.
  • LED (light) treatment of acute, dry macular degeneration.
  • Esophageal cooling device to manage patient temperature.
  • Surgical robotics.
  • Patient positioning system for orthopedic surgery.
  • Device to treat macular degeneration by delivering microcurrent to the eye.

For a historical listing of medtech startup technologies included in the database, see link.

Medtech fundings in August 2014

Fundings in medical technology for the month of August 2014 totaled a tepid $199 million, the largest of which are the $55 million funding of Civitas Therapeutics and the $30 million funding of OptiNose. Below were the top fundings for the month.

Company, funding Product/technology
Civitas Therapeutics, inc. has raised $55.25 million in a round of funding according to a regulatory filing Respiratory drug delivery
OptiNose, Inc., has raised $30 million of a planned $35 million round of funding according to a regulatory filing Powered intranasal drug delivery
Claret Medical, Inc., has raised up to $18 million in a Series B round of funding according to press reports Catheter for cerebral protection during transcatheter aortic valve implantation
Silk Road Medical, Inc., has raised $15 million of a planned $22.5 million round of funding according to a regulatory filing Transcarotid stent for treatment of neurovascular disorders
ViaCyte, Inc., has raised $15 million in a round of funding according to a regulatory filing Cell therapy-based artificial pancreas for diabetes
Seventh Sense Biosystems, Inc., has raised $10.47 million of a planned $16.47 million round of funding according to a regulatory filing Phlebotomy technologies

For the complete list of medtech fundings in August 2014, see link. For a historical list of the fundings in medtech, by month, since 2009, see link.

Medical technologies at startups, July 2014

Below is a list of technologies under development at medical technology startups identified in July 2014 and included in the Medtech Startups Database.

  • thrombectomyInstrumentation for electrophysiology diagnosis and treatment.
  • Products for the treatment of hypertension and other chronic disease by interventional cardiologists
  • Surgical stapling device for use during natural orifice transluminal endoscopic surgery.
  • Low cost medical technologies to improve patient management in emerging markets.
  • Heart valve for the treatment of mitral valve regurgitation
  • Thrombectomy catheter
  • Microstaple bandage for wound closure.
  • Whole-body cryotherapy chambers as well as devices for local cryotherapy and cryosurgery.
  • Minimally invasive surgical device for the treatment of glaucoma
  • Electrical muscle stimulation.

For a historical listing of medical technologies at startups, see link.