Applications of surgical sealants, glues, hemostats in cardiovascular disease

Given the clinical utility of surgical sealants, glues and related products in stopping bleeding, restoring vascular structures and otherwise achieving the goal of restoring vital cardiovascular function, these products have many specific applications in clinical practice, resulting in large potential caseload worldwide.  See the breakdown of case load by type in cardiovascular applications:

Source: MedMarket Diligence, LLC; Report #S190.

Below is a list of selected specific applications (drawn from report #S190) for surgical sealants, glues, hemostats, anti-adhesion and related products for treatment of cardiovascular diseases:

  • Augmentation of aortic and vascular sutures.
  • Repair of minor epicardial lacerations without the use of sutures.
  • Hemostasis and reinforcement of anastomoses of coronary bypass and as an adhesive to optimize and secure the path of coronary bypasses on the heart.
  • Coating of perianeurysmatic tissue in ventricular aneurysm surgery
  • Reinforcement of sutures and patch adhesion in reduction of the left ventricle.
  • As an adhesive to secure the dissection plane in acute aortic dissections.
  • As a hemostatic agent in the prevention of bleeding of proximal and distal anastomoses in acute aortic dissections.
  • As an adhesive for gluing patches for dissected aorta reinforcement.
  • As a hemostatic agent on anastomoses in aortic valve surgery, particularly in the presence of calcific or atheromatous aortas.
  • Hemostasis and reinforcement of sutures after aortic aneurysm repair.
  • In re-operations, as a hemostatic adhesive on lacerations of the ventricle caused by re-sternotomy or the presence of adhesions.

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