The driving force in the market for surgical sealants, glues, wound closure and related products is simply the number of different wound and the need to optimize healing to minimize blood loss, infection and other sequellae, all of which otherwise add to the cost of healthcare.
The predominant form of wounds, by numbers, is surgical wounds; that is, those wounds caused by surgical incision, as opposed to trauma. Given the formation of the wound, the surgical incision, in a carefully controlled manner that accordingly results in clean edges, little or no tissue loss, sterile conditions and other considerations, surgical wounds are most readily healed, typically in less than two weeks. At the other end of the spectrum are chronic wounds, the majority of which are venous, arterial and diabetic ulcers, caused by inadequate blood flow, which is in turn caused by either excess pressure (e.g., "bed" sores) or conditions such as diabetes that are associated with occlusions in small blood vessels.
Below is illustrated the resulting scale, between wound prevalence and healing time, for the range of different wound types. While surgical wounds are high in prevalence and may be expeditiously managed by conventional wound sealing and closure technologies, chronic wounds are much less prevalent, but the costs associated with their ongoing management in efforts to heal them create a big need for effective treatments.
Source: MedMarket Diligence, LLC; Report #S190, "Worldwide Surgical Sealants, Glues, Wound Closure and Anti-Adhesion Markets, 2010-2017."