Surgical sealants, glues, hemostats, staple/clips/sutures, other wound closure and anti-adhesion

Below is the preliminary outline of coverage for the pending 2011/2012 MedMarket Diligence report (#S190) on surgical sealants, glues, hemostats, staples/clips (and other wound closure) and anti-adhesion products.

  • EXECUTIVE SUMMARY
     
  • SECTION 1: CLINICAL NEED, CASELOAD AND PROCEDURE VOLUME
  • 1.1. Anatomy and Physiology of Tissue Repair
  • 1.2. The Skin
  • 1.3. Internal Tissues and Organ
  • 1.4. Wound Classification and Types
    • 1.4.1. Classification by Morphology and Severity
    • 1.4.2. Classification by Cause
    • 1.4.3. Surgical Wounds
  • 1.5. Caseload
    • 1.5.1. Cardiovascular
      • 1.5.1.1. Coronary Heart Disease
      • 1.5.1.2. Dysfunctional Heart Valves
      • 1.5.1.3. Peripheral Vascular Disorders
      • 1.5.1.4. Abnormal Aortic Aneurysms
      • 1.5.1.5. Drivers of Caseloads for Cardiac Surgery
    • 1.5.2. Neurological
      • 1.5.2.1. Stroke
      • 1.5.2.2. Parkinson’s Disease
      • 1.5.2.3. Epilepsy
      • 1.5.2.4. Traumatic Injury
      • 1.5.2.5. Peripheral Nerve Treatment
      • 1.5.2.6. Drivers of Neurological Surgery
    • 1.5.3. Orthopedic
      • 1.5.3.1. Hip Replacement
      • 1.5.3.2. Knee Replacements
      • 1.5.3.3. Cartilage Repair
      • 1.5.3.4. Ligament Damage
      • 1.5.3.5. Bone Grafting
      • 1.5.3.6. Vertebral Disc Repair
      • 1.5.3.7. Drivers of Orthopedic Surgery
    • 1.5.4. Urological
      • 1.5.4.1. Incontinence
      • 1.5.4.2. Drivers of Urological Surgery
    • 1.5.5. Dermatological
      • 1.5.5.1. Burns
      • 1.5.5.2. Pressure Ulcers
      • 1.5.5.3. Diabetic Ulcers
      • 1.5.5.4. Venous Ulcers
      • 1.5.5.5. Plastic Surgery
      • 1.5.5.6. Drivers of Dermatological Surgery
  • 1.6. The Role of Modern Sealant, Securement and Hemostatic Products in Surgery
    • 1.6.1. Fibrin Sealants
    • 1.6.2. High-Strength Glues

       

  • SECTION 2: SCIENCE, TECHNOLOGY, DEVELOPMENT, CLINICAL AND REGULATORY CHALLENGEs
  • 2.1 Tissue Healing
    • 2.1.1 Hemostasis
    • 2.1.2 Proliferation and Maturation
    • 2.1.3 Factors That Affect Healing
  • 2.2 Product Development
  • 2.3 Development Timelines
    • 2.3.1 Collagen and Thrombin Combination
    • 2.3.2 Polyethylene Glycol Polymer (PEG)
    • 2.3.3 Albumin Cross-Linked with Glutaraldehyde
    • 2.3.4 Delivery Systems
  • 2.4 Cost-Effectiveness
  • 2.5 Regulatory Challenges
    • 2.5.1 Approval Processes
    • 2.5.2 History of Product Development
    • 2.5.3 Regulatory Aspects
       
  • SECTION 3: PRODUCTS, TECHNOLOGIES, AND FORECAST OPPORTUNITY
  • 3.1 Overview
    • 3.1.1 Development Timeline
  • 3.2 Sutures, Staples and other Mechanical Closure Devices
    • 3.2.1 Sutures, Staples and Mechanical Closure Competitors and Products
    • 3.2.2 Sutures, Staples and Mechanical Closure Products in Development
    • 3.2.3 Sutures, Staples and Mechanical Closure Market Analysis and Forecast
  • 3.3 Tapes
    • 3.3.1 Medical Tape Competitors and Products
    • 3.3.2 Medical Tape Market Analysis and Forecast
  • 3.4 Hemostats
    • 3.4.1 Hemostat Competitors and Products
    • 3.4.2 Hemostat Products in Development
    • 3.4.3 Hemostat Market Analysis and Forecasts
  • 3.5 Fibrin and Other Sealant Products
    • 3.5.1 Fibrin and Other Sealant Competitors and Products
    • 3.5.2 Fibrin and Other Sealant Products in Development
    • 3.5.3 Fibrin and Other Sealant Market Analysis and Forecasts
  • 3.6 High-Strength Medical Adhesives
    • 3.6.1 High-Strength Medical Adhesive Competitors and Products
    • 3.6.2 High-Strength Medical Adhesive Products in Development
    • 3.6.3 High-Strength Medical Adhesive Market Analysis and Forecasts
  • 3.7 Post-Surgical Adhesion Prevention
    • 3.7.1 Post-Surgical Adhesion Prevention Competitors and Products
    • 3.7.2 Post-Surgical Adhesion Prevention Products in Development
    • 3.7.3 Post-Surgical Adhesion Prevention Market Analysis and Forecasts
  • 3.8 Wound Closure and Securement Markets: Global and Regional Analysis
    • 3.8.1 Americas
    • 3.8.2 European Union
    • 3.8.3 Asia-Pacific
    • 3.8.4 Rest of World
  • 3.9 Worldwide Markets By Country and Segment
    • 3.9.1 Americas
      • 3.9.1.1 United States
        • 3.9.1.1.1 Sutures & Staples
        • 3.9.1.1.2 Mechanical Closure
        • 3.9.1.1.3 Tapes
        • 3.9.1.1.4 Hemostats
        • 3.9.1.1.5 Fibrin & Other Sealants
        • 3.9.1.1.6 High-Strength Medical Adhesives
        • 3.9.1.1.7 Post-Surgical Adhesion Prevention
      • 3.9.1.2 Rest of North America
        • 3.9.1.2.1 Sutures & Staples
        • 3.9.1.2.2 Mechanical Closure
        • 3.9.1.2.3 Tapes
        • 3.9.1.2.4 Hemostats
        • 3.9.1.2.5 Fibrin & Other Sealants
        • 3.9.1.2.6 High-Strength Medical Adhesives
        • 3.9.1.2.7 Post-Surgical Adhesion Prevention
      • 3.9.1.3 Latin America
        • 3.9.1.3.1 Sutures & Staples
        • 3.9.1.3.2 Mechanical Closure
        • 3.9.1.3.3 Tapes
        • 3.9.1.3.4 Hemostats
        • 3.9.1.3.5 Fibrin & Other Sealants
        • 3.9.1.3.6 High-Strength Medical Adhesives
        • 3.9.1.3.7 Post-Surgical Adhesion Prevention
    • 3.9.2 European Union
      • 3.9.2.1 United Kingdom
        • 3.9.2.1.1 Sutures & Staples
        • 3.9.2.1.2 Mechanical Closure
        • 3.9.2.1.3 Tapes
        • 3.9.2.1.4 Hemostats
        • 3.9.2.1.5 Fibrin & Other Sealants
        • 3.9.2.1.6 High-Strength Medical Adhesives
        • 3.9.2.1.7 Post-Surgical Adhesion Prevention
      • 3.9.2.2 Germany
        • 3.9.2.2.1 Sutures & Staples
        • 3.9.2.2.2 Mechanical Closure
        • 3.9.2.2.3 Tapes
        • 3.9.2.2.4 Hemostats
        • 3.9.2.2.5 Fibrin & Other Sealants
        • 3.9.2.2.6 High-Strength Medical Adhesives
        • 3.9.2.2.7 Post-Surgical Adhesion Prevention
      • 3.9.2.3 France
        • 3.9.2.3.1 Sutures & Staples
        • 3.9.2.3.2 Mechanical Closure
        • 3.9.2.3.3 Tapes
        • 3.9.2.3.4 Hemostats
        • 3.9.2.3.5 Fibrin & Other Sealants
        • 3.9.2.3.6 High-Strength Medical Adhesives
        • 3.9.2.3.7 Post-Surgical Adhesion Prevention
      • 3.9.2.4 Spain
        • 3.9.2.4.1 Sutures & Staples
        • 3.9.2.4.2 Mechanical Closure
        • 3.9.2.4.3 Tapes
        • 3.9.2.4.4 Hemostats
        • 3.9.2.4.5 Fibrin & Other Sealants
        • 3.9.2.4.6 High-Strength Medical Adhesives
        • 3.9.2.4.7 Post-Surgical Adhesion Prevention
      • 3.9.2.5 Italy
        • 3.9.2.5.1 Sutures & Staples
        • 3.9.2.5.2 Mechanical Closure
        • 3.9.2.5.3 Tapes
        • 3.9.2.5.4 Hemostats
        • 3.9.2.5.5 Fibrin & Other Sealants
        • 3.9.2.5.6 High-Strength Medical Adhesives
        • 3.9.2.5.7 Post-Surgical Adhesion Prevention
      • 3.9.2.6 Rest of Europe
        • 3.9.2.6.1 Sutures & Staples
        • 3.9.2.6.2 Mechanical Closure
        • 3.9.2.6.3 Tapes
        • 3.9.2.6.4 Hemostats
        • 3.9.2.6.5 Fibrin & Other Sealants
        • 3.9.2.6.6 High-Strength Medical Adhesives
        • 3.9.2.6.7 Post-Surgical Adhesion Prevention
    • 3.8.3 Asia-Pacific
      • 3.8.3.1 Japan
        • 3.8.3.1.1 Sutures & Staples
        • 3.8.3.1.2 Mechanical Closure
        • 3.8.3.1.3 Tapes
        • 3.8.3.1.4 Hemostats
        • 3.8.3.1.5 Fibrin & Other Sealants
        • 3.8.3.1.6 High-Strength Medical Adhesives
        • 3.8.3.1.7 Post-Surgical Adhesion Prevention
      • 3.8.3.2 Korea
        • 3.8.3.2.1 Sutures & Staples
        • 3.8.3.2.2 Mechanical Closure
        • 3.8.3.2.3 Tapes
        • 3.8.3.2.4 Hemostats
        • 3.8.3.2.5 Fibrin & Other Sealants
        • 3.8.3.2.6 High-Strength Medical Adhesives
        • 3.8.3.2.7 Post-Surgical Adhesion Prevention
      • 3.8.3.3 Rest of Asia-Pacific
        • 3.8.3.3.1 Sutures & Staples
        • 3.8.3.3.2 Mechanical Closure
        • 3.8.3.3.3 Tapes
        • 3.8.3.3.4 Hemostats
        • 3.8.3.3.5 Fibrin & Other Sealants
        • 3.8.3.3.6 High-Strength Medical Adhesives
        • 3.8.3.3.7 Post-Surgical Adhesion Prevention
      • 3.8.4 Rest of World
        • 3.8.4.1.1 Sutures & Staples
        • 3.8.4.1.2 Mechanical Closure
        • 3.8.4.1.3 Tapes
        • 3.8.4.1.4 Hemostats
        • 3.8.4.1.5 Fibrin & Other Sealants
        • 3.8.4.1.6 High-Strength Medical Adhesives
        • 3.8.4.1.7 Post-Surgical Adhesion Prevention
           
  • SECTION 4: COMPANY PROFILES
     
  • 4.1 3DM, Inc. (3D-Matrix, Ltd.)
  • 4.2 3M
  • 4.3 Abbott Laboratories
  • 4.4 AccessClosure, Inc.
  • 4.5 Adhezion Biomedical, LLC
  • 4.6 Advanced Medical Solutions Group plc/Medlogic Global
  • 4.7 Aeris Therapeutics
  • 4.8 Angiotech Pharmaceuticals, Inc.
  • 4.9 Anika Therapeutics, Inc.
  • 4.10 ARC Pharmaceuticals
  • 4.11 Arch Therapeutics, Inc.
  • 4.12 ArthroCare Corporation
  • 4.13 Aso LLC
  • 4.14 Aspen Surgical Products
  • 4.15 Avery Dennison
  • 4.16 B. Braun (Braun Melsungen AG)
  • 4.17 Baxter International Inc.
  • 4.18 Berlin Heart GmbH
  • 4.19 Bernsco Surgical Supply (George Tiemann & Co.)
  • 4.20 Biocoral Inc.
  • 4.21 BIOSTER a.s.
  • 4.22 BSN Medical
  • 4.23 C.R. Bard (Bard Medical, Davol)
  • 4.24 Cardiva Medical, Inc.
  • 4.25 Ceremed, Inc.
  • 4.26 Chemence Medical
  • 4.27 Cohera Medical, Inc.
  • 4.28 Collagen Matrix, Inc.
  • 4.29 Coloplast A/S
  • 4.30 Covidien Ltd.
  • 4.31 CryoLife Inc.
  • 4.32 CSIRO PhotoMedical Technologies
  • 4.33 CSL Behring
  • 4.34 CSMG Technologies, Inc. (Live Tissue Connect, Inc.)
  • 4.35 CuraMedical BV
  • 4.36 Derma Sciences, Inc.
  • 4.37 DuPont Applied BioSciences
  • 4.38 Entegrion, Inc.
  • 4.39 FibroGen, Inc.
  • 4.40 Fidia Advanced Biopolymers
  • 4.41 FzioMed Inc.
  • 4.42 Gelita Medical BV
  • 4.43 GEM srl
  • 4.44 Genzyme Biosurgery Inc.
  • 4.45 GluStitch
  • 4.46 Graceduty Company Limited
  • 4.47 Hartmann Group/Hartmann USA
  • 4.48 Harvest Technologies Corporation
  • 4.49 HemCon Medical Technologies, Inc.
  • 4.50 Hemostasis, LLC
  • 4.51 Human BioSciences, Inc.
  • 4.52 HyperBranch Medical Technology, Inc.
  • 4.53 Incisive Surgical, Inc.
  • 4.54 Innovasa Corporation
  • 4.55 Integra Lifesciences Corporation
  • 4.56 Johnson & Johnson (Ethicon, Inc., Ethicon Endo-Surgery, Inc.)
  • 4.57 Kaketsuken (Chemo-Sero-Therapeutic Research Institute)
  • 4.58 Kensey Nash Corporation
  • 4.59 Kimberly-Clark Health Care
  • 4.60 Kinetic Concepts, Inc.
  • 4.61 King Pharmaceuticals, Inc. (Pfizer, Inc.)
  • 4.62 Kookbo Chemicals Co., Ltd. (KB Chem.)
  • 4.63 Laboratoires Urgo (Urgo Medical)
  • 4.64 LifeBond Ltd.
  • 4.65 Lohmann & Rauscher
  • 4.66 Marine Polymer Technologies
  • 4.67 Medafor, Inc.
  • 4.68 MedTrade Products, Ltd.
  • 4.69 Meyer-Haake GmbH Medical Innovations
  • 4.70 Mölnlycke Health Care AB
  • 4.71 Morris Innovative
  • 4.72 Motex Healthcare Corp.
  • 4.73 NeatStitch Ltd.
  • 4.74 Nycomed
  • 4.75 Ocular Therapeutix, Inc.
  • 4.76 Omrix Biopharmaceuticals Inc.
  • 4.77 Pfizer Inc.
  • 4.78 Pharming Group NV
  • 4.79 Piramal Healthcare
  • 4.80 Plasma Technologies, Inc.
  • 4.81 Pluromed, Inc.
  • 4.82 Polyganics
  • 4.83 Polyheal Ltd.
  • 4.84 ProFibrix BV
  • 4.85 Protein Polymer Technologies, Inc.
  • 4.86 Resorba Wundversorgung GmbH & Co. KG
  • 4.87 Scion Cardio-Vascular, Inc.
  • 4.88 Sea Run Holdings
  • 4.89 Smith & Nephew plc
  • 4.90 St. Jude Medical
  • 4.91 Starch Medical, Inc.
  • 4.92 Synovis Life Technologies
  • 4.93 SyntheMed, Inc.
  • 4.94 Teleflex Medical
  • 4.95 ThermoGenesis Corporation
  • 4.96 Thrombotargets Corp.
  • 4.97 Tissuemed Ltd.
  • 4.98 Vascular Solutions, Inc.
  • 4.99 Vectura Group plc
  • 4.100 Vivostat A/S
  • 4.101 Wound Care Technologies, Inc.
  • 4.102 Z-Medica Corporation
  • 4.103 Zimmer
  • 4.104 ZymoGenetics, Inc.
     
  • APPENDIX: COMPANY DIRECTORY

For the complete report description (and to keep updated on publication status), see Report #S190.

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