Clinical applications and markets in cell therapy and tissue engineering

Tissue engineering and cell therapy comprise a market for regenerative products that is expected to grow worldwide from $6.9 billion in 2009 to almost $32 billion by 2018. This market spans many specialties, the biggest of which is therapies for degenerative and traumatic orthopedic and spine applications. Other disorders that will benefit from cell therapies include cardiac and vascular disease, a wide range of neurological disorders, diabetes, inflammatory diseases, and dental decay and/or injury. Key factors expected to influence the market for regenerative medicine are continued political actions, government funding, clinical trials results, industry investments, and an increasing awareness among both physicians and the general public of the accessibility of cell therapies for medical applications.

Cell therapy is defined as a process whereby new cells are introduced into tissue as a method of treating disease; the process may or may not include gene therapy. Forms of cell therapy can include: transplantation of autologous (from the patient) or allogeneic (from a donor) stem cells , transplantation of mature, functional cells, application of modified human cells used to produce a needed substance, xenotransplantation of non-human cells used to produce a needed substance, and transplantation of transdifferentiated cells derived from the patient’s differentiated cells.

Once considered a segment of biomaterial technologies, tissue engineering has evolved into its own category and now comprises a combination of cells, engineering and suitable biochemical and physiochemical factors to improve or replace biological functions. These include ways to repair or replace human tissue with applications in nearly every medical specialty. Regenerative medicine is often synonymous with tissue engineering but usually focuses on the use of stem cells. 

Much of the value of tissue engineering and cell therapy (the latter in particular) clearly resides in the future, when many of the hurdles have been crossed that now limit our ability to leverage the clinical benefits of cell and tissues for treatment of a wide range of diseases.  Be that as it may, the benefits of cell therapy and tissue engineering already comprise a large and rapidly growing therapeutics market.  Below is illustrated the growth of the global tissue engineering and cell therapy segmented by area of clinical application.

Source: "Tissue Engineering, Cell Therapy and Transplantation: Products, Technologies & Market Opportunities, Worldwide, 2009-2018." Report #S520; MedMarket Diligence, LLC.

Leave a Reply

Your email address will not be published. Required fields are marked *

847,299 Spambots Blocked by Simple Comments

HTML tags are not allowed.