Degenerative disc disease (DDD) is one of the most common conditions affecting adults. While it does not always manifest itself in symptoms (it can be seen by MRI in 25% of asymptomatic individuals under 40, and in 60% of asymptomatic individuals over 40), its prevalence in an aging population, in which its prevalence increases, is a big driver of spine surgery procedures. DDD can encompass degradation of bony architecture, discs, or supporting muscles and ligaments of the spine.
Source: Report #M520, "Worldwide Spine Surgery Market 2010-2020."
DDD is addressed surgically by procedures that fuse adjacent vertebra or replace the disc. In the graph are shown these global procedure volumes in 2010 for treatment of DDD.