Please note that the original data on glucose monitoring referenced in the post below was compiled in mid-2010 — considerable change has taken place in the market since then.
One of the fundamental challenges in managing diabetes, especially insulin-dependent diabetes mellitus (or “juvenile onset” diabetes) is the lag between a sharp trend in blood glucose levels (up or down) and the diabetic’s awareness. The sooner a diabetic can become aware of becoming hypo- or hyperglycemic, the sooner he/she can act to preempt this adverse affects, some of which (especially for hypoglycemia) can be dangerous.
Couple this with another fundamental challenge in diabetes — the need for painful, frequent blood glucose testing involving finger pricks for blood sampling — and it becomes clear why continuous blood glucose monitoring (cBGM), especially non-invasive, holds potential. While the challenge of providing cBGM is currently more economic than technical, as a practical matter the solution has not yet emerged that is supported by industry.
Below (and in response to an inquiry from a Quora member) is a 2010 listing (perhaps in need of a recent update) of manufacturers developing continuous blood glucose monitors.
Developers of Continuous Blood Glucose Monitors
|Abbott||FreeStyle Navigator||Advanced hypo- and hyperglycenia alarms. Has integrated FreeStyle meter for calibration||Approved|
|AiMedics Pty Ltd.||HypoMon||Noninvasive, electro-physiological, chest skinÐbased||In development|
|ArKal Medical||(Unnamed)||Improved convenience and ease||In development|
|Biorasis Inc. (aka Bio-Orasis)||Glucowizzard||Implantable sensor||In development|
|Cascade Matrix, Inc.||Based on the AutoSampler automated vascular blood sampling system||Noninvasive mid-infrared/microfluid||Developmental|
|DexCom, Inc.||SEVEN, SEVEN PLUS||Can be worn up to 7 days||Approved|
|Echo Therapeutics (formerly Sontra Medical)||Symphony tCGS||Noninvasive (needle-free), wireless, transdermal, sonophoresis||In pilot trials|
|GluMetrics, Inc.||GluCath||Single-use catheter and sensor system for real-time intravenous monitoring of patientÕs glucose; for hospital use||In development|
|Medtronic||iPro 2 Professional||Disposable glucose sensor. Small automatic data recorder. Small, lightweight, watertight. Allows 288 readings in 24 hour period, uploadable via internet for remote access||CE Mark, launched outside the U.S.in June 2010, approval pending in 22 other countries|
|Medtronic||Paradigm REAL-Time||Paradigm CGM combined with Minimed pump||Approved|
|Medtronic||Guardian REAL-Time||CGM only||Approved|
|Menarini||GlucoDay S||For type 1 and type 2 diabetics||Approved in Europe|
|Roche||SCGM1||Glucose measurement at 5 min intervals for up to 4 days. Microdialysis-based measurement||Investigational|
|Ultradian Diagnostics||Biologue||Wireless, predict and alarm user 20 minutes of a high or low glucose level, calibration-free interface to an insulin pump||In development|
Source: Report #D510, “Diabetes Management: Products, Technologies, Markets and Opportunities Worldwide 2009-2018″, Report #D510.