Among the armamentaria that a modern clinician has at his disposal is a wide range of product types for closing, sealing, adhering or even preventing the tissue adhesion of wounds. The list has evolved as manufacturers continue to formulate wound closure products that can demonstrate optimum wound healing. This includes minimizing infection, stopping bleeding, structurally holding incisions or traumatic sites together under increasing stress, minimizing the toxicity of wound sealant or adhesive, accelerating the healing time and other functions.
Below is illustrated a table (sortable by product type in the column headings) of the manufacturers of different products for producing hemostasis.
Hemostat Manufacturers by Product Type
|Indications / Procedures||2015||2016||2017||2018||2019||2020||2021||2022||CAGR 2016-2022|
|Total EVAR AAA/TAA Procedures||15||16.3||17.6||18.9||20.2||21.5||22.8||24.1||6.70%|
|Diagnosed AAA & TAA Caseloads||165||170||175||180||185||190||195||200||2.80%|
|Treated AAA & TAA Patients||56||58.5||61||63.5||66||68.5||71||73.5||3.90%|
|Abdominal Aortic Aneurysm (AAA) Repair|
|Treated AAA Patient Caseloads||45||47||49||51||53||55||57||59||3.90%|
|Surgical Repair Procedures||33||34||35||36||37||38||39||40||2.80%|
|Endovascular Repair Procedures||12||13||14||15||16||17||18||19||6.50%|
|Thoracic Aortic Aneurysm (TAA) Repair|
|Treated TAA Patient Caseloads||11||11.5||12||12.5||13||13.5||14||14.5||3.90%|
|Surgical Repair Procedures||8||8.2||8.4||8.6||8.8||9||9.2||9.4||2.30%|
|Endovascular Repair Procedures||3||3.3||3.6||3.9||4.2||4.5||4.8||5.1||7.50%|
|Total Surgical AAA/TAA Repairs||41||42.2||43.4||44.6||45.8||47||48.2||49.4||2.70%|
Source: MedMarket Diligence, LLC; Report #S180, "Worldwide Surgical Sealants, Glues, Wound Closure and Anti-Adhesion Markets, 2010-2015."
The market for hemostats (currently at about $1.5 billion globally) is dynamic as multiple product types are adapted to new clinical applications, which surgeons and other clinicians are increasingly prepared to use. Since the early 1990s, when surgical sealants, glues and hemostats started to be more widely used in the United States (following uncharacteristically early adoption that was higher in Japan due to a more heightened concern by the FDA about viral transmission in these products, the majority of them being blood-based products), the market has proliferated with double digit annual growth spanning well over a decade.