Fibrin sealants, fibrin glues, high strength glues (cyonacrylates, bioglues, etc.), and other securement products have their most immediate opportunity in the treatment of integumentary conditions – ulcers, lacerations/plastic surgery and burns. Â The ease of access to these chronic or surgical wounds, by a wide range of specialists, the reduced technical challenge (including lack of internal toxicity issues of cyanoacrylates) and other factors give rise to significant volume of potential patients.
While cosmetic/plastic surgery applications have declined commensurate with the global recession’s pinch on unreimbursed procedures, there remains an aggregate caseload of potential integumentary applications worldwide of nearly 16 million.
Source: MedMarket Diligence, LLC; Report #S180
Following dermal applications, the next most readily accessible set of procedures fall in the area of general surgery, which comprise a high volume of caseload from the following specific ones (see Report #S180):
- As an adhesive in both traditional and laparoscopic inguinal hernia plastic surgery with patches.
- Hemostasis of liver section slices.
- Hemostasis of the bleeding gallbladder bed in traditional and laparoscopic surgery.
- Gluing, repair and hemostasis of parenchymal tissue on lacerations or hemorrhagic lesions of the liver, kidney, pancreas, or spleen.
- Sealing and reinforcement of gastrointestinal anastomoses.
- Hemostasis of portacaval anastomoses.
- Sealing of appendix stump.
- Sealing in rectovaginal septum reconstruction.
- Sealing of anastomoses in biliary tract and pancreatic duct reconstruction.
- Treatment of axillary and inguinal lymphorrhoea.