Potential for sealants, glues and other securement in dermal repair, general surgery

Fibrin sealants, fibrin glues, high strength glues (cyonacrylates, bioglues, etc.), and other securement products have their most immediate opportunity in the treatment of integumentary conditions – ulcers, lacerations/plastic surgery and burns.  The ease of access to these chronic or surgical wounds, by a wide range of specialists, the reduced technical challenge (including lack of internal toxicity issues of cyanoacrylates) and other factors give rise to significant volume of potential patients.

While cosmetic/plastic surgery applications have declined commensurate with the global recession’s pinch on unreimbursed procedures, there remains an aggregate caseload of potential integumentary applications worldwide of nearly 16 million.

Source: MedMarket Diligence, LLC; Report #S180

Following dermal applications, the next most readily accessible set of procedures fall in the area of general surgery, which comprise a high volume of caseload from the following specific ones (see Report #S180):

  • As an adhesive in both traditional and laparoscopic inguinal hernia plastic surgery with patches.
  • Hemostasis of liver section slices.
  • Hemostasis of the bleeding gallbladder bed in traditional and laparoscopic surgery.
  • Gluing, repair and hemostasis of parenchymal tissue on lacerations or hemorrhagic lesions of the liver, kidney, pancreas, or spleen.
  • Sealing and reinforcement of gastrointestinal anastomoses.
  • Hemostasis of portacaval anastomoses.
  • Sealing of appendix stump.
  • Sealing in rectovaginal septum reconstruction.
  • Sealing of anastomoses in biliary tract and pancreatic duct reconstruction.
  • Treatment of axillary and inguinal lymphorrhoea.