Manufacturers of Surgical Sutures, Staples, Clips, and Other Mechanical Closure Devices

The vast majority of sutures, staples and endostaples are used following procedures involving acute surgical wounds. Typically, chronic wounds do not involve use of suture and staple products unless some degree of surgical intervention is employed to remove necrotic tissue or to create a new acute wound bed to aid healing.

Sutures comprise two component parts, the needle and the suture, and these can be found in a wide range of sizes and types, made of a range of materials, and the method of attachment of the suture to the needle can involve a variety of methods. Sutures are divided into braided and monofilament categories. Braided sutures are typically more pliable than monofilament and exhibit better knot security. Monofilament sutures are more wiry and may require a more secure knot. Their major advantage is that they cause less tissue drag, a characteristic that is especially important in cardiovascular, ophthalmic and neurological surgery. Over the last few years, some companies have developed devices (such as Abbott Vascular’s Perclose, ProGlide and Prostar suture-mediated devices) that can complete the suturing process and tie the finishing knot quickly.

Stapler devices can be seen as an evolution of suture technology. The goal of stapler products is to avoid infection, remove some of the difficulty of skillful suturing, and make total procedures quicker and easier. Staples are made of stainless steel and biomaterials and are used to join internal tissues, reconstruct or seal off organs, remove diseased tissue, occlude blood vessels, and close skin incisions. They are primarily used during surgery as internal and/or external closure devices.

Staples are available in an assortment of sizes and features; procedure-specific stapler devices have been developed to take staple clips for use in one specific procedure or for multiple uses. Internal staplers are used to approximate internal tissues and organs. The devices may be reusable or disposable. Some disposable staplers may be reloaded several times during the course of a single patient surgical procedure and then discarded.

suture-staples-clipsThe most recent internal staplers are used to perform minimally invasive surgical procedures that allow the surgeon to endoscopically secure internal wounds instead of having to operate through an open procedure. Staples can be made to dissolve, and this obviates the need for removal; these staples are ideally suited to laparoscopic surgery and delivered via procedure-specific laparoscopic instruments. However, most staples are still made of stainless steel and when used for internal stapling procedures, whether open or laparoscopic, are not removed after healing. Skin staples are removed after the incision is healed.

Perhaps the major benefit of staples is that they can be applied more rapidly than sutures and can be placed precisely without requiring the skill necessary for sutures. This also means increased safety for the patient, and patients can often be discharged more rapidly as a result of stapling procedures.

While cosmetically acceptable results are usually obtained, staplers normally are not used in highly visible areas such as the face. Here surgeons will still close by hand to minimize any scarring. In many procedures, sutures have begun to be replaced by cyanoacrylate glues, but the ideal alternative to suturing has not yet been developed; for example, cyanoacrylate glues used for external skin closure are only one-fifth as strong as sutures.


Source:  MedMarket Diligence, LLC; Report #S175.

The market for surgical sutures, staples, clips and other mechanical closure are analyzed in the global market for these and competitive/complementary products in the report, "Worldwide Surgical Sealants, Glues and Wound Closure Market, 2009-2013". 

6 thoughts on “Manufacturers of Surgical Sutures, Staples, Clips, and Other Mechanical Closure Devices”

  1. Dear sir/madam.
    Eight months ago i was operated on to repair an abdominal anuysem in the renal area so it was a major op, and my incition was across my uper stomack just under my chest bone [20 inches long] and it still feels tender especialy when i sneeze or cough, how long will it take to heal so i dont feel it anymore, it is also numb in places.
    Kind regards Mr Ash

  2. Because of the size (and depth of the incision), the tenderness may last for some time. Sneezing and coughing can be fairly tough on the abdomen, too, so the tenderness may last for a while (another year?). Keep in mind, as you well know, that you have had a major condition addressed in the repair of the aneurysm, so don't be too impatient about the healing. Many people unfortunately never even know about abdominal aneurysms until it is too late.

  3. Hello Sir,

    Thanks you for your kind explanation regarding to Sutures/Staplers etc for a Lehman like me.
    I am from UK, working in a Investment Bank, I want to get into small Pharma related business to start with.
    One of my friend suggested me about sutures/Steplers. I have gone through each of the manufacturer you have mentioned in the list. But I reckon, these are massive companies and I am not sure if they will manufacture the product on my brand name.
    I would really appriciate if you could help me in finding the manufacturer. Please kindly share me your details so that we can have a detailed discussions.

    Kind Regards,
    Meetkle

  4. If you are looking at sutures and staples, you really need to understand the competitive landscape for wound closure product manufacturers. There is the complete spectrum of companies involved in that marketplace from pre-start ups with technologies at the proof in principles of stage to large multinational manufacturers with diverse product portfolios to everything in between. That is the subject of our report on surgical sealants, glues, wound closure and anti-adhesion. See http://www.mediligence.com/rpt/rpt–s190.htm.

  5. Dear sir/Madam. As we are one of the leading firms engaging in medical devices and medicine in IRAN. Hereby we have a substantial order in relevant to various high performance quality of surgical ENDOSTAPLER products, although it should necessarily has obtained FDA approval. In this respect, we have an adequate number of well- qualified experts and fully prepared to put above mentioned products in a large scale on our market, therefore, could you please lead or match us with such a suppliers in USA OR EUROPE preferably?
    Your kind help would be highly appreciated.

  6. In response to your inquiry, this blog covers medical technology markets and their relevant trends and opportunities. If you are seeking to import products to your country, our recommendation is that you directly contact the manufacturers (of which there are many!) of the specific products of interest to you. They will then be able to advise you on the opportunities for your import efforts.

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