Nanoparticles are yet another weapon in the arsenal of alternatives being developed for treatment of coronary artery disease (as we note in report #C245).
The Surat-based Concept Medical Research Private Limited (CMRPL) has applied for patent in India and the US for introducing nano particles to release drugs to block cell proliferation in the narrowed diseased coronary arteries. Manish Doshi, president and Chief Executive Officer (CEO), CMRPL told Newsline: There are no biotechnologists in India or in any other country who have used nanotechnology to release drugs into the diseased coronary arteries. The drugs are generally released through drug-eluting stents. The stents are bio-absorbable but are made of polymers. If the polymer remains in the diseased artery for long, it may result in inflammation, clotting and toxicity, thereby leading to further complications. As such, there are instances of complications arising after angioplasty.