New medical technologies at startups identified in 2008-2009

Below is a list of the products and technologies at companies detailed in the Medtech Startups Database that have been identified in 2008 and 2009.  (This is a detailed list that is more convenience accessed via an online subscrption to the database; see link above.)

  • Nanoparticle-based delivery of chemotherapeutic agents for cancer.
  • MRI-guided robotic breast cancer intervention.
  • Materials to enhance in situ tissue regeneration.
  • Device technology to reduce incisions in laparoscopic surgery.
  • Ophthalmic technologies targeting vision loss.
  • Motion preserving spine fusion implant, inserted minimally invasively, for treatment of degenerative disc disease.
  • Treatment of neurological and psychiatric disorders by, for example, electrical stimulation.
  • Developing technologies to visualize vascular junctions in order to enhance ablation in treatment of atrial fibrillation.
  • Device technologies to enhance left ventricular assist device (LVAD) implantation.
  • Femoral head resurfacing implant with internal fixation and instrumentation.
  • Ophthalmic device technologies.
  • Developing a device for retro-muscular mesh placement in hernia repair.
  • Integrated insulin pump and glucose monitor for insulin-dependent diabetes.
  • Technologies for embolic cerebral protection to reduce embolic stroke during interventional procedures.
  • Device for opening obstructed airways (cricothyroidotomy) following traumatic injuries.
  • Medical devices R&D company.
  • Endovascular treatment of neurovascular disorders.
  • Medical devices
  • Weight loss therapeutic developer
  • Surgical instruments, including blunt dissection and tissue elevation instrument.
  • Developing cryotherapy and cryosurgery ablation devices. It focuses on benign tumor and tissue ablation.
  • Diabetes diagnostics; ocular-based blood glucose measurement.
  • Implant technologies for peripheral nerve repair.
  • Device to ease the pain of compression fractures of the spine by separating spinal bones and injecting fast-hardening cement.
  • Biological cartilage regeneration and endoscopic spine surgery
  • Biomaterials technologies for multiple medical device applications.
  • Low-frequency ultrasound in wound healing.
  • Microwave ablation of liver, kidney and lung tumors.
  • Diagnosis of pediatric vesicoureteral reflux.
  • Developing atherectomy for peripheral vascular disease.
  • Systems to facilitate arthroscopic surgery.
  • Bioimplants for surgery.
  • Novel instrumentation for use in laparoscopic surgery.
  • Interbody spacers for spine surgery.
  • Electrosurgical instrumentation.
  • Drug startup
  • Pediatric therapeutics
  • Non-surgical treatment of obesity via outpatient device implant.
  • Biomaterials for soft tissue repair
  • Developing automated glucose measurement system based on near infrared.
  • Products in OB/GYN, orthopedics and aesthetics.
  • Device to non-invasively monitor intracranial pressure.
  • Acquired vascular business of Smith & Nephew
  • Unique cell-derived growth factor to attract stem cells and stimulated tissue regeneration in damaged heart tissue.
  • Stents (tantalum, zirconium, niobium, and/or tungsten)
  • Nanotechnology-based gene therapy for congestive heart failure.
  • Ultrasound catheter
  • Undisclosed technology
  • Soft tissue repair products and products used in soft tissue repair procedures
  • Design and development of medical devices for vascular access site hemostasis
  • Knee alignment system to preserve knee surfaces and restore normal activity.
  • Device to detect changes in the endothelium to potentially predict coronary artery disease and stroke.
  • Orthopedic and spinal anchoring implants for use in spine surgery.
  • Device for treatment of chronic head and neck pain.
  • Medical device company launched by Paragon Innovations.
  • Device and methods to treat low back pain.
  • Medical device technology platform company focused on cardiovascualr applications, including a percutaneous venous valve, inferior vena cava filter, laparoscopic scissor grasper, and Parodi guidewire.
  • Mesh device technologies to facilitate laparoscopic surgery.
  • Mineral-based hemostatic compound for use in stopping arterial bleeding.
  • Stents and other device technologies for interventional use.
  • Novel advanced damaged tissue care systems.
  • Devices to facilitate knee replacement
  • Devices for less invasive removal of tumors from brain and central nervous system tissue.
  • Synthetic scaffolds for tissue regeneration
  • Family of clear liquids comprised of nanoscale peptides that self-assemble into a gel to stop bleeding following injury or during surgery.
  • Endovascular treatments for peripheral artery disease.
  • Devices for interventional radiology and neuroradiology markets, including stroke.
  • Undisclosed medical device technology in development.
  • Implantable graft for aortic heart valve repair.
  • Orthopedic soft tissue and skeletal repair.
  • M.inimally invasive implants for the treatment of osteo-arthritis
  • Intra-operative radiographic margin assessment in breast cancer surgery.
  • Developing innovative devices for treatment of various neurovascular diseases, including stroke and cerebral aneurysm.
  • Regenerative medicine spin-out from the U.S. Dept. of Energy’s Oak Ridge National Laboratory (ORNL) developing method to restore functioning tissue to damaged hearts.
  • Sensor materials company
  • Neuroscience company applying EEG to development of sleep apnea monitoring and other applications.
  • Development of retraction technology and other improvement in surgical instrumentation.
  • Percutaneous access and visualization of the spine for diagnosis and/or treatment.
  • Implantable Microelectrodes for Neurological Disorders
  • Developing novel devices for the treatment of diabetes.
  • Synthetic cartilage for joint repair.
  • Spine surgery products.
  • Developing a total joint replacement system for the lumbar spine incorporating a artificial lumbar disc and posterior dynamic stabilization device.
  • Stent, coating process and disease model for evaluating cardiovascular interventions.
  • Nanotechnology-based biosensors.
  • Proprietary formulations of sealants and hemostats for use in traumatic wounds and surgery.
  • Contraceptive device for transcervical reversible cornual sterilization.
  • Cardiovascular devices including coronary and peripheral stents.
  • Spine surgical technology including a cervical distraction device.
  • Automated wearable artificial kidney.
  • Neurostimulation for cardiac contractility.
  • Guidewire technology for endovascular navigation.
  • Interspinous processes for treatment of spine disorders.
  • Percutaneous interventional devices for the treatment of spinal disease including lumbar spinal stenosis.
  • Minimally invasive spinal implants
  • Acoustic device for spine surgery.
  • Protein-based plastics including bioresorbable bone graft
  • Ultrasound-guided endosurgical devices.
  • Cancer therapeutics
  • Device to block pathogen transmission via intravenous catheters.
  • Surgical drain and other technologies.
  • Device for treatment of chronic obstructive pulmonary disease (COPD)
  • Undisclosed medical device technology.
  • Self-expanding stent for femoral and popliteal applications.
  • Nitric oxide coatings for blood-contacting medical devices.
  • Intervertebral implant to control vertebrae spacing in order to alleviate leg and lumbar pain.
  • Diagnosing and treating diseases and injuries to the spine by injecting drugs into the diseased or injured area.
  • Orthopedic implants
  • Bioresorbable implants for a range of surgical applications.
  • Wound closure device designed to reduce scarring while maintaining closure strength.
  • Novel wound healing and drug-delivery based on proprietary hydrogel.
  • Undisclosed medical device technology.
  • Infection control devices.
  • Recombinant proteins and cells for inter vertebral disc cell regeneration.
  • Non-hydrogel polymer used to stimulate tissue growth in dental/orthopedic applications.
  • Biomaterials and biologics for repair of bone and cartilage.
  • Portable endoscopic imaging.
  • Bariatric, endoscopic and other GI devices.
  • Human bionic devices for physical dysfunctions.
  • Device treatments for restless leg syndrome (RLS).
  • Devices to exploit the autonomic nervous system to alleviate pain and treat disease.
  • Stem cell-based therapeutics for neurologic diseases including Parkinson’s.
  • Neuromodulation for treatment, initially, of urinary incontinence.
  • Spinal implant technologies.
  • Disposable steerable surgical instrumentation for arthroscopy.
  • Technologies to restore spinal disc function.
  • Embolic protection system.
  • Development of pluripotent stem cells for drug discovery and regenerative medicine.
  • Laser devices to "weld" biological tissues together for wound closures.
  • Drug-coated urinary and other catheters and stents that are designed to prevent or treat scar tissue.
  • Rib fracture plating system
  • Artificial heart technologies.
  • Heart pumps.
  • Compliant balloon technologies.
  • Diagnostic and therapeutic ophthalmic devices.
  • Developing implantable medical devices for the treatment of spine disorders.
  • Device for mitral valve repair without need for sternotomy.
  • Pharmaceutical treatments for ischemia and vascular disease, focused on peripheral artery disease.
  • Non-polymeric drug eluting stent
  • Focusing on developing products to improve surgical outcomes, focusing on cardiac, orthopedic and vascular surgeries. #oct08#
  • Device technology in diabetes management.
  • Neurostimulation of pain for patients with neuroma or phantom limb pain.
  • Medical device inflatables, including devices for biological navigation such as in support of colonoscopy and other endoscopy.
  • Minimally-invasive products for motion-preserving spine surgery.
  • Minimally invasive treatment of vertebral compression fractures.
  • Device for treating pain associated with osteoarthritis of the knee.
  • Minimally invasive treatments for removing varicose veins.
  • Drug-coated angioplasty for coronary and peripheral applications
  • Fully implantable artificial heart.
  • Biomaterials for use in aesthetic surgery.
  • Mesh used to improve patency in saphenous vein grafts for CABG.
  • New vascular devices for use on patients that undergo procedures with a high risk of blood vessel blockage.
  • Treatments and diagnostics for orthopedics.
  • Devices for cardiac surgery, including a device for performing structured sternal incisions.
  • Handheld diagnostic device detecting cancer cells via fluorescing enzyme, performed following tumor removal to detect residual cancer.
  • Ambulatory cardiac monitoring.
  • Ophthalmic diagnostic and therapeutic device.
  • Minimally invasive RF tissue welding technology for use in lung resection and biopsy.
  • Innovative technologies to treat heart valve disease.
  • RealView imaging capsule, a minimally invasive endoscopic device for long-term monitoring of bladder cancer (transitional cell carcinoma).
  • Self-propelled colonoscope that retains the therapeutic capabilities of a standard colonoscope.
  • Polymer-based absorbable surgical hemostats.
  • Spinal implant manufacturer
  • Nanotechnology biomaterials company developing angiogenic materials for use in wound management, treatment of ischemic heart disease, others.
  • Medical device company backed by Flagship Ventures, Polaris Venture Partners and Third Rock Ventures.
  • Surgical irrigation and retraction systems.
  • Devices based on piezoelectric, magnetorestrictive and shape memory materials technologies, including a sonicator and an ophthalmic surgical device.
  • Surgical dressings
  • Autologous fluid concentrator
  • Intraoperative nerve location and protection device.
  • Peripheral nerve stimulation for treatment of post-stroke shoulder pain.
  • Medical device to prevent surgical site infections in orthopedic and spinal surgeries.
  • Biocompatible, thermoplastic materials for osteosynthesis
  • Pain management
  • Minimally invasive spine technologies
  • Developing novel treatments for Gastro-Intestinal disorders.
  • Developing an innovative treatment for patients with osteoarthritis.
  • Image guided laparoscopy system
  • Orthopedic implants
  • Provider of products for the orthopaedic device market, formed via the merger of two existing companies
  • Developing device to diagnose abnormal joint conditions via ultrasound.
  • Seed stage company within a VC firm developing a low profile stent graft for the treatment of abdominal aortic aneurysms (AAA).
  • Stealth medical device company
  • Soft tissue regeneration of the anterior cruciate ligament (ACL) of the knee.
  • Near infrared-based venous imaging system
  • Embolic protection device
  • Bioactive, polymer materials and coatings for medical devices to improve biocompatibility, safety, and improve MRI compatibility.
  • External fixation for leg bone fractures.
  • Devices for minimally invasive spine surgery
  • Tissue preservation for orthpedic applications
  • Nanoparticle-based immunomodulatory drugs.
  • Pharmaceutical preparations for treatment of obesity.
  • Drug-eluting balloons.
  • Implantable shunt for draining fluid, such as for synovial fluid.
  • Undisclosed ophthalmic devices.
  • Proprietary system to assist orthopedic surgeons in the delivery of long bone intramedullary nail implants.
  • Adult stem cell technology for treatment of stroke, traumatic brain injury, wound care, neurodegenerative diseases and diseases of the eye.
  • Advanced damaged tissue care systems for wound care.
  • Devices in interventional cardiology.
  • Coronary artery augmentation system to prevent need for reoperation of clotted grafts.
  • Bio prosthetic devices including cardiovascular stents.
  • Drug delivery (insulin pump) technology for diabetes.
  • Implantable glucose sensor for glucose monitoring in diabetes.
  • Surgical instrumentation
  • Wound dressings and wound fillers.
  • Non-invasive drug delivery via transdermal patch.
  • Wireless stimulation device for treatment of chronic pain.
  • A self-regulating, dual-pump, continuous flow Total Artificial Heart System.
  • Intraarterial ventricular assist device.
  • Non-invasive back pain device.
  • Left ventricular cardiovascular support.
  • General surgical tools.
  • Micro-robotic imaging and surgical device technology to facilitate minimally invasive surgeries.
  • "Cell bandage" technology for repair of damaged knee meniscus.
  • Glucose sensor and regulation technology
  • Undisclosed medical devices.
  • Therapeutic cardiovascular devices.
  • Catheter technologies.
  • Orthopedic attachment and fixation.
  • Orthopedic joints (hip, knee, shoulder), fracture fixation and other devices.
  • Electromechanical orthopedic implant to alleviate leg and lumbar pain.
  • Percutaneous mitral valve replacement.
  • Femtosecond lasers for cataract surgery.

 

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